Tailoring viral vector transgene optimization for enhanced efficacy

Live30 webinars are thirty minute presentations designed to update you on the latest innovations, applications and data in a fast yet interactive format.

Transgene optimization often takes a “one size fits all” approach that uses the same optimization process irrespective of a transgene’s desired expression profile. Rather, factors unique to each vector’s use case should be considered during optimization.

This webinar discusses the Expression Cassette Optimization (ECO) platform as an AI-driven optimization tool that considers the gene transfer vector, target tissue, and real-world manufacturing constraints to output optimized sequences tailored to each transgene’s desired expression profile. The potential to achieve high-titer viral vector manufacture using this platform will be explored, specifically through leveraging of fixed bed bioreactor technology.

Attend this webinar to discover:

• The why and how of AI-driven therapeutic transgene optimization
• How to achieve enhanced therapeutic efficacy through targeted tissue/cell expression
• What is the impact of transgene cassette optimization on viral vector manufacturing

Harrison Brown

Director of Computational Biology Expression Therapeutics