Process development optimization for GMP manufacturing: A CAR-T case study

Live30 webinars are thirty minute presentations designed to update you on the latest innovations, applications and data in a fast yet interactive format.

In this webinar, we will discuss the importance of PD optimization and some of the key considerations such as: choosing a partner for outsourcing PD projects, the timing needed for a typical PD project, technology and process transfer to GMP manufacturing, etc.

Finally, we will review a case study for Lentiviral manufacturing which is required upstream of an autologous CAR-T clinical trial. The duration, sequence and dependencies of these two distinct PD projects, and their subsequent GMP manufacturing campaigns, will be examined.

• Understand the timing and planning process for a typical process development process to achieve GMP manufacturing.
• Learn more about process development capabilities to support cGMP manufacturing.
• Review a case study for Lentiviral manufacturing, supporting CAR-T.

Gary Pigeau PhD

Director of Research and Development, Nucleic Acid Therapeutics, Cytiva